Charles Jiang/utswmed.org
Feb 20, 2025, 08:33
Charles Jiang: Big news in prostate cancer treatment
Charles Jiang, Medical Oncologist at UT Southwestern, shared a post on X:
“Big news in prostate cancer treatment:
- Two major studies show promising results for estradiol patches as an alternative to traditional hormone therapy.
- The patch method could mean fewer side effects while still effectively treating cancer.”
“How it works:
- Traditional hormone therapy (LHRH agonists) lowers both testosterone.
- AND estrogen, leading to challenging side effects.
- The patch maintains healthy estrogen levels while still lowering testosterone—potentially offering better quality of life.”
“Key findings from the PATCH trial in early-stage prostate cancer:
- Controls testosterone as effectively as standard treatment.
- Fewer hot flashes reported.
- May help protect bone health.
- Similar cancer control outcomes.”
“The STAMPEDE trial studied patients with advanced prostate cancer:
- Confirmed benefits seen in PATCH trial.
- Significant reduction in severe hot flashes.
- Better bone health outcomes.
- Comparable effectiveness to current treatments.”
“What this means for patients:
- A potentially more tolerable treatment option.
- May be more cost-effective.
- Could be especially helpful for those struggling with side effects (hot flashes!).
- This might be right for your patients.”
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