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Cesar Perez: Preliminary Phase 2 data for vilastobart in combination with atezolizumab for advanced MSS CRC
Jan 28, 2025, 09:11

Cesar Perez: Preliminary Phase 2 data for vilastobart in combination with atezolizumab for advanced MSS CRC

Cesar Perez, Director of Drug Development at Lake Nona DDU of Florida Cancer Specialists and Research Institute, shared on LinkedIn:

“We presented the Preliminary Phase 2 data for vilastobart (XTX101), a tumor-activated, Fc-enhanced, high affinity binding anti-CTLA-4, in combination with atezolizumab in patients with advanced MSS CRC

– 40 patients with MSS CRC enrolled in ongoing Phase 2

– 18 response-evaluable patients with at least 1 scan reported

– Low incidence of immune colitis (5%)

– 3 of 11 patients without liver metastatic disease had partial response (27%) 

To be continued …”

Cesar Perez: Preliminary Phase 2 data for vilastobart in combination with atezolizumab for advanced MSS CRC