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Erman Akkus: Acquired Resistance to FGFR inhibitors in Cholangiocarcinoma
Dec 24, 2024, 11:09

Erman Akkus: Acquired Resistance to FGFR inhibitors in Cholangiocarcinoma

Erman Akkus, Medical Oncology fellow at Ankara University, shared a poston X:

“Acquired Resistance to FGFR inhibitors in Cholangiocarcinoma.

  • Acquired resistance: via secondary FGFR2 mutations in >60% of patients with clinical benefit
  • low achievable drug concentrations in humans >emergence of resistance
  • FGFR inhibitors should be small, high-affinity, selective
  • Tinengotinib.”

Erman Akkus: Acquired Resistance to FGFR inhibitors in Cholangiocarcinoma

More posts featuring Erman Akkus.

Erman Akkus is a medical oncology fellow at the Ankara University, Faculty of Medicine. Previously, he was an Internal Medicine Resident at the Ankara University, Faculty of Medicine. He was also a Visiting Researcher at the University of Oslo. He completed his education from the Medical University of Vienna.