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Rachna T. Shroff: SWOG S1815 shows no OS benefit for nab-paclitaxel in BTCs
deptmedicine.arizona.edu/news/2023/dr-rachna-shroff-selected-lead-hematology-and-oncology-division
Dec 16, 2024, 08:37

Rachna T. Shroff: SWOG S1815 shows no OS benefit for nab-paclitaxel in BTCs

Ben Westphalen, Chair of Translational Research and Precision Medicine Working Group at ESMO, shared an article by Rachna T. Shroff et al. on X, adding the following:

“Open Access in JCO ASCO

SWOG S1815 found no OS or PFS benefit for adding nab-paclitaxel to gemcitabine-cisplatin (GAP vs GC) in advanced biliary tract cancers (BTCs). Median OS: 14.0 vs 13.6 months (P=0.41). GAP showed more toxicity.”

SWOG S1815: A Phase III Randomized Trial of Gemcitabine, Cisplatin, and Nab-Paclitaxel Versus Gemcitabine and Cisplatin in Newly Diagnosed, Advanced Biliary Tract Cancers

Authors: Rachna T. Shroff, Gentry King, Sarah Colby, Aaron J. Scott, Mitesh J. Borad, Laura Goff, Khalid Matin, Amit Mahipal, Aparna Kalyan, Milind M. Javle, Imane El Dika, Benjamin Tan, Puneet Cheema, Anuj Patel, Renuka Iyer, R. Katie Kelley, Jaykumar Thumar, Anthony El-Khoueiry, Katherine A. Guthrie, E. Gabriela Chiorean, Howard Hochster, Philip A. Philip

Rachna T. Shroff: SWOG S1815 shows no OS benefit for nab-paclitaxel in BTCs

advanced biliary cancer Ben Westphalen Biliary tract cancers BTC research cancer cancer trials GAP vs GC gemcitabine-cisplatin JCO ASCO nab-paclitaxel OncoDaily Oncology overall survival progression-free survival SWOG S1815
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