Myeloma Paper of the Day, November 19th, suggested by Robert Orlowski
Robert Orlowski shared a post on X:
“Myeloma Paper of the Day: Early dFLC response by C1D7 (67.0% change, optimal sensitivity 87.5%, specificity 81.3%) may predict complete hematologic response and organ response in systemic AL amyloidosis and may allow for early modification of therapy.”
Early dFLC response by C1D7 predicts complete hematologic response in systemic AL amyloidosis
Authors: Yang Liu, Jingyi Bi, Xuelin Dou, Nan Peng, Lei Wen, Yanqiu Zhao, Xiaojun Huang, Jin Lu.
More posts featuring Robert Orlowski.
Robert Orlowski, M.D., Ph.D., holds multiple positions at The University of Texas MD Anderson Cancer Center, including Chairman, Ad Interim Director of Myeloma, and Professor of Medicine in the Departments of Lymphoma/Myeloma and Experimental Therapeutics within the Division of Cancer Medicine. Additionally, he chairs the SWOG Barlogie/Salmon Myeloma Committee, which is part of the National Clinical Trials Network, dedicated to advancing new therapies and understanding the biology of myeloma.
Dr. Orlowski’s expertise lies in both clinical practice and scientific research, with a particular focus on translating laboratory discoveries into effective treatments for patients. He investigates drug resistance mechanisms in myeloma and seeks to identify predictive biomarkers for treatment response. Notably, his past contributions include leadership roles in developing proteasome inhibitors like bortezomib and carfilzomib, as well as monoclonal antibodies such as daratumumab and elotuzumab.
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