Elvina Almuradova: “Oncofetal ecosystem” in HCC linked to early relapse after surgery

Elvina Almuradova, Associate Professor at Medicana Health Group, shared a post on X about a paper by Ziyi Li et al. published in Nature Cancer.

“Presence of onco-fetal neighborhoods in hepatocellular carcinoma is associated with relapse and response to immunotherapy”

Authors: Ziyi Li, Rhea Pai, Saurabh Gupta, Pierce Kah-Hoe Chow, Florent Ginhoux, Ankur Sharma et al.

“Researchers found an ‘oncofetal ecosystem’ in HCC involving POSTN+ CAFs, linked to early relapse after surgery. Patients with strong oncofetal signatures responded better to immunotherapy.”

Source: Elvina Almuradova/X