Aaron Goodman: CMV drugs!

Aaron Goodman posted the following on X:

“CMV drugs!

Ganciclovir
GCV-phos -> DNA
WBC

Foscarnet
Mimic of pyrophosphate interferes with exchange in DNA
Nephrotoxicity, electrolytes

Cidofovir CDV-phos -> DNA
Nephrotoxicity/Fanconi syndrome

Letermovir = PPx
Targets CMV DNA terminase (pUL56)
Limited toxicity.”

Source: Aaron Goodman/X

Aaron Goodman is a Hematologist/ Oncologist and an Associate Professor of Medicine at the University of California, San Diego. He is a member of the National Comprehensive Cancer Network (NCCN) guideline committee for both cutaneous NHLs and T-cell NHLs. Dr. Goodman is a well-known physician-scientist, educator, advocate, and social media influencer.