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Vince Luca: The structure of LAG3 bound to MHC-II
Sep 2, 2024, 12:56

Vince Luca: The structure of LAG3 bound to MHC-II

Vince Luca, Associate Professor at Moffitt Cancer Center, shared on X:

“I am excited to share our Nature Communications paper describing the structure of LAG3 bound to MHC-II. This project was carried out by Qianqian Ming et al. at Moffitt Research and provides new insights into the mechanism by which LAG3 suppresses T cell activation.”

Structural basis for mouse LAG3 interactions with the MHC class II molecule I-Ab

Authors: Qianqian Ming, Daniel Antfolk, David A. Price, Anna Manturova, Elliot Medina, Srishti Singh, Charlotte Mason, Timothy H. Tran, Keiran S. M. Smalley, Daisy W. Leung and Vincent C. Luca.

Vince Luca: The structure of LAG3 bound to MHC-II

Source: Vince Luca/X