Vince Luca: The structure of LAG3 bound to MHC-II

Vince Luca, Associate Professor at Moffitt Cancer Center, shared on X:

“I am excited to share our Nature Communications paper describing the structure of LAG3 bound to MHC-II. This project was carried out by Qianqian Ming et al. at Moffitt Research and provides new insights into the mechanism by which LAG3 suppresses T cell activation.”

Structural basis for mouse LAG3 interactions with the MHC class II molecule I-Ab

Authors: Qianqian Ming, Daniel Antfolk, David A. Price, Anna Manturova, Elliot Medina, Srishti Singh, Charlotte Mason, Timothy H. Tran, Keiran S. M. Smalley, Daisy W. Leung and Vincent C. Luca.

Source: Vince Luca/X