New insights into calcineurin’s role in T-cell receptor signalling – NCI Center for Cancer Research

NCI Center for Cancer Research shared a post on LinkedIn about a recent paper by Shizuka Otsuka et al., commenting:

“New Findings: CCR researchers recently revealed new insights into calcineurin’s role in T-cell receptor (TCR) signaling. Calcineurin is a protein phosphatase that plays many important roles in the body.

This finding was led by Jonathan D. Ashwell, who recently became a National Institutes of Health (NIH) Scientist Emeritus in the Laboratory of Cellular and Molecular Biology. Before his retirement, his lab worked to understand the physiologic and pathologic regulation of signaling in T cells.”

Calcineurin is an adaptor required for assembly of the TCR signaling complex published in National Library of Medicine.

Authors: Shizuka Otsuka, Debjani Dutta, Chuan-Jin Wu, Muhammad S Alam, Jonathan D.

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Source: NCI Center for Cancer Research/LinkedIn