Susumu Kobayashi: The importance of BCL-XL during emergence of resistance to EGFR TKIs

Susumu Kobayashi, Associate Professor at Harvard Medical School, shared a post on X about a recent paper by Motohiro Izumi et al. titled “Integrative single-cell RNA-seq and spatial transcriptomics analyses reveal diverse apoptosis-related gene expression profiles in EGFR-mutated lung cancer” published in Cell Death and Disease.

Authors: Motohiro Izumi, Masanori Fujii, Ikei Kobayashi, Vivian Ho, Yukie Kashima, Hibiki Udagawa, Daniel Costa and Susumu Kobayashi.

“Our new paper is out. This paper highlights the importance of BCL-XL among BCL2 family proteins during emergence of resistance to EGFR TKIs.”

Source: Susumu Kobayashi/X