Abhishek D. Garg/LinkedIn
Jul 20, 2024, 11:34
Abhishek D. Garg: TIM3+VISTA+ macrophage subset that mediates resistance to anticancer immunotherapy and chemotherapy
Abhishek D. Garg,
“Thrilled to share our lab’s latest research on an unique, evolutionarily conserved, TIM3+VISTA+ macrophage subset that mediates widespread resistance to anticancer immunotherapy as well as chemotherapy!
Source: Abhishek D. Garg/LinkedIn
Abhishek D. Garg
anticancer immunotherapy
cancer
chemotherapy
Dirk Daelemans
Faculteit Geneeskunde KU Leuven Faculty of Medicine
FWO Research Foundation Flanders
Isaure Vanmeerbeek
Jannes Govaerts
Jenny Sprooten
Joren Verelst
KU Leuven
Leuven Cancer Institute
Louis Boon
Maarten Jacquemyn
Martyna Pociupany
Massimiliano Mazzone
OncoDaily
Oncology
Raquel Laureano
Research Foundation Flanders - FWO
Rosa Trotta
Sabine Tejpar
Samantha Pretto
Sarah Trusso Cafarello
Shikang Zhao
Stand Up Against Cancer
Stefan Naulaerts
Susan Schlenner
UZ Leuven
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ESMO 2024 Congress
September 13-17, 2024
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ASCO Annual Meeting
May 30 - June 4, 2024
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Yvonne Award 2024
May 31, 2024
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OncoThon 2024, Online
Feb. 15, 2024
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Global Summit on War & Cancer 2023, Online
Dec. 14-16, 2023
Dec 21, 2024, 22:40
Dec 21, 2024, 22:37
Dec 21, 2024, 22:26
Dec 21, 2024, 19:39
Dec 21, 2024, 19:21
Dec 21, 2024, 19:19
Discovered via our innovative reverse translational approach! We found that these macrophages enriched in neoantigen negative tumours ONLY in BOTH mouse and humans, and their signature served as a negative prognostic and predictive biomarker in cancer patients!
This brilliant work was made possible because of a series of collaborators and our lab mates, especially the lead author Isaure Vanmeerbeek! Thanks also to Jenny Sprooten, Stefan Naulaerts, Raquel Laureano, Jannes Govaerts, Louis Boon, Susan Schlenner, Sabine Tejpar, Dirk Daelemans, Massimiliano Mazzone and others!
Thanks also to all our funders, sponsers and supporters: KU Leuven, Research Foundation Flanders – FWO, FWO Research Foundation Flanders, Faculteit Geneeskunde KU Leuven Faculty of Medicine ,UZ Leuven, Leuven Cancer Institute, Stand up Against Cancer!
Thanks also to BioTuring for supporting our computational research!
‘Targeting conserved TIM3+VISTA+ tumor-associated macrophages overcomes resistance to cancer immunotherapy’ Published in Science Advances
Authors: Isaure Vanmeerbeek, Stefan Naulaerts, Jenny Sprooten, Raquel Laureano , Jannes Govaerts, Rosa Trotta, Samantha Pretto, Shikang Zhao, Sarah Trusso Cafarello, Joren Verelst, Maarten Jacquemyn, Martyna Pociupany, ouis Boon, Susan Schlenner, Sabine Tejpar, Dirk Daelemans, Massimiliano Mazzone, And Abhishek D. Garg.”