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David Heredia: LEOPARD Study Highlights Early NSCLC Recurrence
Aug 28, 2025, 15:55

David Heredia: LEOPARD Study Highlights Early NSCLC Recurrence

David Heredia, Head of the Oncology Department at Punta Medica, shared a post on X:

”In the real-world LEOPARD study (stage III NSCLC): 56% recurred after chemoradiotherapy plus Durvalumab.

Timing:

  • 53% within first 12 cycles,
  • 25% between 12–24,
  • 22% after 24 cycles.

72% had oligorecurrence.

Most relapses were limited and early, suggesting opportunity for local approaches.”

Title: Locally advanced NSCLC: overview of real-world pattern of recurrence in durvalumab era (LEOPARD trial)

Authors: P. Ciammella, F. Iori, P. Borghetti, M. Galaverni, E. Alì, M. Tiseo, M. Pagano, M. Sepulcri, V. Scotti, N. Giaj Levra, M. Marcenaro, N. Simoni, V. Nardone, A. Bottin, S. Cozzi, A. Bruni

You can read the Full Article on Lung Cancer.

David Heredia

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