Highlights from 2025 SGO Annual Meeting on Women’s Cancer

From March 14 to March 17, Seattle, Washington, hosted the SGO Annual Meeting on Women’s Cancer, the leading conference for professionals dedicated to gynecologic cancer care. Since 1969, the Society of Gynecologic Oncology (SGO) has been bringing together experts from around the world to share the latest research, engage in meaningful discussions, and advance the field of gynecologic oncology.

This year’s meeting attracted a diverse group of specialists, including gynecologic, medical, and radiation oncologists, pathologists, OB/GYNs, nurses, pharmacists, physician assistants, fellows, residents, medical students, and patient advocates. Beyond the scientific sessions and educational programs, the event provided invaluable networking opportunities, allowing attendees to connect, collaborate, and exchange ideas.

The meeting also featured an impressive lineup of exhibitors from leading medical device and pharmaceutical companies, showcasing cutting-edge innovations in gynecologic cancer care. Sponsorships for various events and services further enhanced the experience, making it a well-rounded and engaging conference.

The 2024 meeting was chaired by Dr. Alexander Olawaiye, Dr. Victoria Bae-Jump, Dr. Paola Gehrig, and Dr. Sean Dowdy. Among the invited speakers were Jonathan Perlin, Liz Wiseman, Gretchen Schwarze, and Monica Bertagnolli, who shared their insights and expertise, contributing to the meeting’s success.

A key highlight of the event was Dr. Karen Lu stepping into her new role as SGO President, marking an exciting new chapter for the organization.

Year after year, the SGO Annual Meeting plays a crucial role in shaping the future of gynecologic oncology by fostering collaboration, innovation, and education. This year was no exception, reinforcing the importance of coming together as a community to improve cancer care and outcomes.

Our team at OncoDaily has also curated key highlights from the SGO 2025 that you won’t want to miss.

Karen Lu:

“Sachia Powell giving an impactful speech on giving back as an ovarian cancer patient – she’s partnering and encouraging our ovarian cancer scientists!

Powell-Drescher Ovarian Cancer Research Foundation has an incredible mission – check it out!”

Shannon Westin:

“Azenosertib (WEE1i) has high activity in CCNE1 positive recurrent ovarian cancer.

Design trials based on the right science and you get great results!

Incredibly durable response – 34.9% in IHC positive tumors!”

Ying Liu:

“Help prevent “missed opportunities” in ovarian cancer.

Sara Moufarrij found that 15-23% of patients with HGSOC had surgery where opportunistic salpingectomy (OS) was missed.

Kara Long and others are raising awareness. We need data to guide patients!”

Moffitt Cancer Center:

“During the SGOMtg, Moffitt Physician-in-Chief Karen Lu joins Hye Sook Chon, to discuss the role of immunotherapy in treating endometrial cancer, based on the latest research presented at the meeting.”

Society of Gynecologic Oncology:

“Healthcare as a global industry ranks as the fifth-largest producer of greenhouse gases—an urgent call to action.

In today’s Focused Forum, Jonathan Perlin, MD, PhD, MSHA, MACP, FACMI, President and CEO of The Joint Commission Enterprise, delivered a powerful case for sustainable healthcare, emphasizing the connection between environmental responsibility, human health, and patient safety. His message was clear: prioritizing sustainability isn’t just ethical—it’s essential for the future of healthcare.

A powerful reminder from Dr. Perlin’s talk:

‘Of all the forms of inequality, injustice in health is the most shocking and the most inhuman because it often results in physical death.– Martin Luther King Jr.'”

Ying Liu:

“Superstar Maria Rubinstein presenting the impressive results of DB1305, a TROP2 targeting ADC, in ovarian cancer at SGO2025.

Aggressive management of stomatitis makes this treatment tolerable and keeps our patients going!”

Núria Agustí Garcia:

“Great presentation on our JAMA Network Open study about surgical trends and future directions in our field! Even better to share this experience in such a beautiful city with wonderful colleagues.”

Kristin Taylor:

“This window of opportunity trial demonstrated an 80% complete response rate to neoadjuvant ICI in resectable dMMR endometrial cancer!

Could this be an emerging option for fertility-sparing or medically frail patients?”

Luis Felipe Falla:

“Ending on a great focus.

Dr. Oluloro from the UW Department of Obstetrics and Gynecology reminded us how systemic racism is a root cause and driver of health inequities in the US.

A call for action.”

Karen Lu:

⁦”Erin George presenting CCNE1 amplification occurs in a subset of HGS ovarian cancer and uterine serous cancer.

Co-mutations with p53 and non-immunogenicity.”

Sergei Iugai:

“New pathways are emerging for targeted therapies in gynecologic tumors—glucocorticoid receptors, what an interesting twist!

An exciting morning session on overcoming platinum resistance in ovarian cancer at SGO2025.”

Ying Liu:

“Dr. Chinmayi showing data from Myriad Genetics on ancestry-based differences in VUS findings in >80k patients with ovarian cancer.

We need to include more diverse women in genetic testing and only make recs for pathogenic variants!”

Taro Yamanaka:

“Luveltamab tazevibulin (novel FolRα-targeting ADC) in PROC — REFRαME-O1 Phase 2/3:

• ORR: 30.8% (PS2+ ≥75%), 33.3% (PS2+ <75%),
• Manageable safety, with reduced neutropenia incidence using G-CSF prophylaxis,
• Phase 3 ongoing.”

Joshua Garrett Cohen:

“Thank you Dr. Nickles Fader and Dr. Gardner for your leadership with SGO and The Foundation for Women’s Cancer to unite the efforts of SGO and the FWC under a synergistic mission to eradicate gynecologic cancer and train the next generation of providers.”

Shannon Westin:

“6 methylated DNA marker (MDM) panel yielded high sensitivity to detect endometrial cancer from vaginal fluid.

This represents an exciting potential option to avoid painful endometrial biopsy for assessment of abnormal uterine bleeding.”

Nicole D. Fleming:

“Empowering story from our SGO President Amanda Nickles Fader with a personal connection to Seattle and Fred Hutchinson Cancer Center helping to drive her passion and mission as an expert leader and impact player in our field!”