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Keeping up with WLC25 by Estela Rodriguez
Feb 3, 2025, 12:57

Keeping up with WLC25 by Estela Rodriguez

The 22nd Annual Winter Lung Cancer Conference (WLC25) took place from Friday, January 31, 2025 to Sunday, February 2, 2025 in Hollywood, FL.

22nd Annual Winter Lung Cancer Conference®

Estela Rodriguez, Associate Director of Community Outreach and Co-Lead of Thoracic Site Disease Group of the Sylvester Comprehensive Cancer Center, shared a few highlights from the event:

The winning argument:

Susan Combs Scott knocked it out of the park, winning argument that osimertinib monotherapy is no longer the 2025 standard for 1L EGFR+ NSCLC (highlighting FLAURA2 and MARIPOSA trials).”

Keeping up with WLC25 by Estela Rodriguez

The champion of memes:

Truly the champion of MEMEs. Balazs Halmos argues that single agent Osimertinib is still a standard for 1L EGFR+ NSCLC. Arguing

  • less cost
  • better QOL/less toxicity ( rash and time toxicity)
  • salvage options available.”

Keeping up with WLC25 by Estela Rodriguez

KEAP1/ STK11 biomarkers of resistance to IO therapy:

Master talk by Ferdinandos Skoulidis on KEAP1/ STK11 biomarkers of resistance to IO therapy.

  • KEAP1 drives resistance to chemo
  • STK11 better response to double checkpoint IO”

Keeping up with WLC25 by Estela Rodriguez

The need for palliative care:

Dr Jennifer Kapo outlines the skills needed for oncologists to provide palliative care counseling in clinic. Given high need and shortage of palliative specialists, it is critical for oncologists to master these skills and create a team of support.”

Keeping up with WLC25 by Estela Rodriguez

Primary resistance to ALK TKIs:

Excellent case presented by Coral Olazagasti discussing ALK+ lung cancer primary resistance to ALK TKIs and what to do when our usual therapies stop working.

Key points :

  • repeat biopsies and NGS is key
  • refer to clinical trials early
  • discuss palliative care”

Multidisciplinary Tumor Board Case Discussions:

Multidisciplinary Tumor Board Case discussion w a dream team of experts discussing mgmt of multiple GGOs with Dr David Harpole, Patricia Rivera, Dr Russell Hales with question by Dr Kubicek.”

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For more updates by Dr Rodriguez, visit her X profile here.