Tom Powles: Highlights From ESMO26 on Renal Cancer
Tom Powles/X

Tom Powles: Highlights From ESMO26 on Renal Cancer

Tom Powles, Head of Solid Tumor Research at Barts Cancer Institute, shared on X:

“Renal cancer highlights ESMO26

  1. Final OS data for LS11 (Lenvatinib/belzutifan vs cabo in pretreated disease) & final OS for KN564 (adjuvant pembro vs placebo) by Toni Choueiri
  2. 1st line triplet data for Len/pembo/bel vs Len/pembro/CTLA4 vs Len/pembro by Brian Rini Press release shows it’s negative. Triplets appear hard in RCC.
  3. New monotherapy data for Ivanesimab (VEGF/PD1) and more data. Combination trials to follow
  4. A randomised phase II of metastasis-directed therapy +/- pembro by Roberto Iacovelli

Finally phase 2 data of ENPP3/CD3 T cell engager.”

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Tom Powles: Highlights From ESMO26 on Renal Cancer