Rahul Banerjee: Can GEP Refine High-Risk Myeloma Criteria? Myeloma-XI Says Yes
Rahul Banerjee, Assistant Professor at the Fred Hutchinson Cancer Center and at the University of Washington, shared a post on X about a paper by Sina Alexandra Beer et al. published in Blood:
“Provocative Blood Myeloma-XI trial analysis!
The raison d’être of HR MM criteria is to prevent early relapse. 2025 IMS/IMWG criteria are better, but can GEP go the final mile to identify functional HR MM?
Evidently, yes! Only 2/135 truly unexpected FHRMM when both are used.
I am admittedly a Luddite with GEP in practice (more of a ‘scaredOfInsuranceDenial-ite’)… but this is a great and timely argument for its SOC incorporation.
Unanswered q: Will higher maintenance help for GEP-HR?
Excellent work by Beer Martin Kaiser et al.”
Martin Kaiser, Professor of Haematology at the Institute of Cancer Research, and Consultant Haemato-Oncologist at The Royal Marsden NHS Foundation Trust, shared this post, adding:
“Many thanks, Rahul! At least some insurers are coming around and realise that the (one-off!) upfront cost of better diagnostics can be a mutually useful, patient-centric long-term investment. Considering treatment adaptation based on MRD is much safer when knowing the risk better.”
Title: Challenging the Concept of Functional High-Risk Myeloma through Transcriptional and Genetic Profiling
Authors: Sina Alexandra Beer, David A Cairns, Charlotte Pawlyn, Dr, Amy Elizabeth Holroyd, Elsa Ferris, Gordon Cook, Mark Drayson, Kevin D Boyd, Paula Zuzanna Proszek, Faith E Davies, Ruth M de Tute, Matthew W Jenner, Gareth J Morgan, Roger G. Owen, Michael J Hubank, Richard S. Houlston, Graham H Jackson, Martin F Kaiser
You can read the Full Article on Blood.
More posts featuring Rahul Banerjee.
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Challenging the Status Quo in Colorectal Cancer 2024
December 6-8, 2024
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ESMO 2024 Congress
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ASCO Annual Meeting
May 30 - June 4, 2024
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Yvonne Award 2024
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OncoThon 2024, Online
Feb. 15, 2024
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Global Summit on War & Cancer 2023, Online
Dec. 14-16, 2023