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Rahul Banerjee: Pooled Data for Dose Mods from DREAMM-7 and DREAMM-8
Aug 7, 2025, 16:46

Rahul Banerjee: Pooled Data for Dose Mods from DREAMM-7 and DREAMM-8

Rahul Banerjee, Assistant Professor at Fred Hutchinson Cancer Center at the University of Washington, shared a post on X by Robert Orlowski, Deputy Chair of Lymphoma/Myeloma, Vice Chair of MM Research, and Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, adding:

Great Blood Advances paper by María-Victoria Mateos, Meletios Athanasios Dimopoulos et al: pooled data for dose mods from DREAMM-7 and -8.

With bela-maf in Multiple Myeloma, dose de-escalations are not the exception… they are the norm!

Over 70% of pts with responses had ≥3 separate dose interruptions in both trials.”

Rahul Banerjee

Quoting Robert Orlowski‘s post:

Myeloma Paper of the Day: Modification of belantamab mafodotin dosing to balance efficacy and tolerability in DREAMM-7 and DREAMM-8 trials still produced median PFS in patients with ≥1 dose delay of ≥12 weeks of 36.6 months and NR, respectively.”

Title: Modification of Belantamab Mafodotin Dosing to Balance Efficacy and Tolerability in the DREAMM-7 and DREAMM-8 Trials

Authors: Maria-Victoria Mateos, Suzanne Trudel, Hang Quach, Pawel Robak, Meral Beksac, Ludek Pour, Marek Hus, Kihyun Kim, Vera Zherebtsova, Sosana Delimpasi, Tomas Jelínek, Christopher Ward, P Joy Ho, Vladimir I Vorobyev, Marcelo Pitombeira Lacerda, Gracia Aparecida Martinez, Ivan Spicka, Jakub Radocha, Michele Cavo, Claudio Cerchione, Chengcheng Fu, Kazuhito Suzuki, Rachel Rogers, Amy Phillips-Jones, Zhaohui Wang, Hena Baig, Jodie Wilkes, Xiaoou L Zhou, Eric Lewis, Lydia Eccersley, Neal Sule, Prani Paka, Joanna B Opalinska, Pralay Mukhopadhyay, Vania Tietsche de Moraes Hungria, Meletios Athanasios Dimopoulos

You can read the Full Article in the National Library of Medicine.

Robert Orlowski

More posts featuring Rahul Banerjee and Robert Orlowski on OncoDaily.