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Pablo Sanchis: How the Bone Tumor Microenvironment Drives Osteopontin Expression in Metastatic Prostate Cancer
Aug 9, 2025, 10:22

Pablo Sanchis: How the Bone Tumor Microenvironment Drives Osteopontin Expression in Metastatic Prostate Cancer

Pablo Sanchis, Postdoctoral Intern at MD Anderson Cancer Center, shared a post on X he and colleagues co-authored:

“Check out our work Oncogene unveiling how the bone TME drives Osteopontin expression in metastatic prostate cancer and its association with resistance to AR signaling blockade.”

Title: PKA-driven SPP1 activation as a novel mechanism connecting the bone microenvironment to prostate cancer progression

Authors: Pablo Sanchis, Agustina Sabater, Julia Lechuga, Jimena Rada, Rocio Seniuk, Gaston Pascual, Mora Gatti, Juan Bizzotto, Peter D. A. Shepherd, Jun Yang, Javier Cotignola, Elba Vazquez, Joaquin Mateo, Pia Valacco, Estefania Labanca, Christopher Logothetis, Geraldine Gueron, Nicolas Anselmino

Read The Full Article at Oncogene.

Pablo Sanchis: How the Bone Tumor Microenvironment Drives Osteopontin Expression in Metastatic Prostate Cancer

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