New Research Explores the Cost of Managing Brain Metastases in ALK-Positive Lung Cancer – Oncogene Cancer Research
Oncogene Cancer Research

New Research Explores the Cost of Managing Brain Metastases in ALK-Positive Lung Cancer – Oncogene Cancer Research

Oncogene Cancer Research shared on LinkedIn:

“Brain metastases are one of the complications people with ALK+ and other forms of lung cancer worry about most.

New UK research puts a figure on what preventing them could mean.

Researchers at Pfizer’s health economics team and Dr Shobhit Baijal at the University Hospitals Birmingham NHS Foundation Trust modelled NHS costs of managing ALK-positive advanced NSCLC, with and without brain metastases, using data from four major trials. Published in Lung Cancer Management.

  • First-year NHS cost with brain metastases: £14,870 per person
  • Without brain metastases: £4,133
  • Savings linked to lorlatinib (lower brain metastasis rates in trials) grew over time

From a patient perspective, this isn’t really about pounds and pence – brain metastases carry a real quality-of-life cost alongside the clinical risk.

Health systems need to look at the full picture.”

Title: Cost of managing brain metastases in patients with ALK+ advanced NSCLC with first-line tyrosine kinase inhibitors in the UK

Authors: Hannah Le, Daniel Ladino, Chrissy Lowry, Nada Rifi, Shobhit Baijal

Read the article

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