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Nina Niu Sanford Shared NOM-3 Study Results
Aug 12, 2025, 15:30

Nina Niu Sanford Shared NOM-3 Study Results

Nina Niu Sanford, Assistant Professor and Chief of Gastrointestinal Radiation Oncology at Harvard/Brigham and Women’s Hospital/Massachusetts General Hospital, shared a post on X about a paper by Agnieszka Żółciak-Siwińska et al. published in the Radiotherapy and Oncology:

Short course RT > FOLFOX x 3 > brachy (10Gy x 2) in T2-T4, small N+ rectal cancer.

Organ pres 53%, ~OPRA but << OPERA, likely due to T4 and lower brachy dose.

Brachy can achieve Complete Response with less chemo for lower risk patients, but operator dependent, resource-limited, and trials smaller/heterogeneous.”

Title: Endorectal high-dose-rate brachytherapy boost in rectal cancer: Results of the prospective cohort NOM-3 study on the watch-and-wait strategy

Authors: Agnieszka Żółciak-Siwińska, Lucyna Pietrzak, Ewa Wrońska, Anna Hołdakowska, Aleksandra Kapała, Leszek Zając, Marek Szczepkowski, Karol Paciorek, Bartłomiej Skrzypiec, Wojciech Michalski, Joanna Socha, Krzysztof Bujko

You can read the Full Article in the Radiotherapy and Oncology.

Nina Niu Sanford

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