January, 2025
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2 Neoadjuvant chemo-IO trials for high-risk ER+ BC
Jan 23, 2025, 13:56

2 Neoadjuvant chemo-IO trials for high-risk ER+ BC

Paolo Tarantino, Advanced research fellow at Dana-Farber Cancer Institute, shared an article by Fatima Cardoso on X:

“Simultaneous Nature Medicine publications of 2 neoadjuvant chemo-IO trials for high-risk ER+ BC: KN-756 & CM-7FL.

Both found a striking improvement in pCR rate with IO, with larger Δ if PD-L1+ or low ER.

Waiting for EFS data, which will most likely impact practice.”

2 Neoadjuvant chemo-IO trials for high-risk ER+ BC

Pembrolizumab and chemotherapy in high-risk, early-stage, ER+/HER2 breast cancer: a randomized phase 3 trial.

Authors: Fatima Cardoso, et al.

 2 Neoadjuvant chemo-IO trials for high-risk ER+ BC