Robert Orlowski, Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, shared on X:
“Myeloma Paper of the Day:
Molecular predictors of MRD in NDMM txd w/ quadruplets leads to multimodal random forest model integrating genomic, transcriptomic & epigenomic features which predict MRD w/ AUC 0.77, outperforming clinical/genomic models.”
Title: Molecular predictors of minimal residual disease in newly diagnosed multiple myeloma treated with quadruplet therapy
Authors: Florence Magrangeas, Mia Cherkaoui, Victor Bessonneau-Gaborit, Jennifer Derrien, Céline Chevalier, Catherine Guérin-Charbonnel, Benjamin Diamond, Mehmet Kemal Samur, Intergroupe Francophone du Myélome (IFM), Cyrille Hulin, Denis Caillot, Lionel Karlin, Bertrand Arnulf, Ola Landgren, Nikhil C. Munshi, Hervé Avet-Loiseau, Ludovic Martinet, Jill Corre, Aurore Perrot, Philippe Moreau, Cyrille Touzeau, Stéphane Minvielle, Eric Letouzé
You can read the full article on Nature Medicine.
You can find other articles featuring Robert Orlowski on OncoDaily.