Robert Orlowski, Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, shared on X:
“Myeloma Paper of the Day:
Clonotypic characterization of clonal expansion and intra-tumor heterogeneity in IgM MGUS finds CD9, JCHAIN, RASSF6, DUSP22 main markers of dominant B-cell clone at GEP and chromatin levels, w/ CD9 in PC-like tumor cells.”
Title: Clonotypic characterization defines B-cell drivers of clonal expansion and intratumor heterogeneity in IgM monoclonal gammopathies
Authors: David F. Moreno, Ferran Nadeu, Marta Casado-Peláez, Caterina Mata, Ian Márquez-López, Marco A. Fernández, Sergi Vaqué, Elena Medina, Helena Llobregat, Marta Garrote, Joan Mañé, Oriol Cardús, Luis Gerardo Rodríguez-Lobato, Anna de Daniel, María Teresa Cibeira, Theo Gremen Oliveira, Elizaveta Kulaeva, Ester Lozano, Dolors Colomer, Laura Rosiñol, Ruben van Boxtel, Manel Esteller, Carlos Fernández de Larrea
You can read the full article on HemaSphere.
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