Myeloma Paper of the Day, July 31st, Suggested by Robert Orlowski

Myeloma Paper of the Day, July 31st, Suggested by Robert Orlowski

Robert Orlowski, Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, shared on X:

Myeloma Paper of the Day:

Activating RARβ w/ ATRA may help overcome immunomodulatory drug resistance in t(4;14) myeloma via reduced chromatin accessibility, H3K27 acetylation in FGFR3 promoter, FGFR3 expression, and suppressed PI3K/AKT signaling.

Title: Activating RARβ to overcome immunomodulatory drug resistance in t(4;14) human myeloma

Authors: Ling Zhong, Qiang Wang, Miao Xian, Jianfei Qian, Chuanchao Zhang, Wei Wu, Qi Guo, Yufei Zhang, Rui Duan, Youli Zu, Sunil Mathur, Robert Z. Orlowski, Fenghuang Zhan, Qing Yi

You can read the Full Article on Leukemia.

Myeloma Paper of the Day, July 31st, Suggested by Robert Orlowski

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