Robert Orlowski, Deputy Chair of Lymphoma/Myeloma, Vice Chair of MM Research, and Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, shared a post on X:
“Myeloma Paper of the Day:
Reprogramming glutamine metabolism using CAR-T cells engineered to increase glutamine uptake by expression of the glutamine transporter Asct2 enhances BCMA-CART cell fitness and therapeutic efficacy in myeloma lab models.”
Title: Reprogramming glutamine metabolism enhances BCMA-CART cell fitness and therapeutic efficacy in multiple myeloma
Authors: Flor Navarro, Teresa Lozano, Andrea Fuentes-García, Inés Sánchez-Moreno, Marta Larrayoz, Pedro Justicia, Beatriz Perucha, Maialen Martinez-Tabar, Rebeca Martinez-Turrillas, Noelia Casares, Celia Martín-Otal, Marta Gorraiz, Erin W Meermeier, Marta Chesi, Douglas Lake, Paul Leif Bergsagel, Eva Santamaría, Maria Erendira Calleja-Cervantes, Patxi San Martín-Úriz, Lorea Jordana-Urriza, Xabier Agirre, Sandra Hervas-Stubbs, Juan Roberto Rodriguez-Madoz, Jose A Martínez-Climent, Felipe Prosper, Juan J Lasarte
You can read the Full Article in Blood.
You can find more posts featuring Robert Orlowski on OncoDaily.
