Myeloma Paper of the Day

Myeloma Paper of the Day, August 28th, Suggested by Robert Orlowski

Robert Orlowski, Deputy Chair of Lymphoma/Myeloma, Vice Chair of MM Research, and Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, shared a post on X:

“Myeloma Paper of the Day:

Pre-treatment with iberdomide and dex in Vk*MYC mouse model reshapes bone marrow T cell compartment, promotes infiltration of naive T cells, and generates 100% response rates and long survival in subjects with high tumor burden.”

Title: An immunostimulatory CELMoD combination overcomes resistance to T-cell engagers caused by a high multiple myeloma burden

Authors: Erin W Meermeier, Kirsten Pfeffer, Caleb K Stein, Meaghen Sharik, Megan Tien Du, Yuliza Tafoya Alvarado, Chang-Xin Shi, Yuan Xiao Zhu, Peter Leif Bergsagel, Marta Chesi

You can read the Full Article on Blood.

Myeloma Paper of the Day, August 28th, Suggested by Robert Orlowski

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