Science

Aug 13, 2025, 15:48

Myeloma Paper of the Day, August 13th, Suggested by Robert Orlowski

Robert Orlowski, Deputy Chair of Lymphoma/Myeloma, Vice Chair of MM Research, and Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, shared a post on X:

“Myeloma Paper of the Day:

Germinal center kinase inhibition enhances iberdomide’s anti-myeloma effects by promoting IKZF1 degradation via a CRBN-independent mechanism in both in vitro and in vivo models.”

Title: GCK inhibition enhances iberdomide antimyeloma effects by promoting IKZF1 degradation via a CRBN-independent mechanism

Authors: Shirong Li, Josefine Krüger, Guifen Liu, Huihui Ma, Michael S. Hughes, Rajshekhar Chakraborty, Divaya Bhutani, Markus Y. Mapara, Christophe Marcireau, Suzanne Lentzsch, Jing Fu

You can read the Full Article on Blood Neoplasia.

Myeloma Paper of the Day, August 13th, Suggested by Robert Orlowski

You can find more posts featuring Robert Orlowski on OncoDaily.

blood neoplasia cancer Christophe Marcireau Divaya Bhutani Guifen Liu Huihui Ma Jing Fu Josefine Krüger Markus Y. Mapara Michael S. Hughes Myeloma Myeloma Paper of the Day OncoDaily Oncology Rajshekhar Chakraborty Robert Orlowski Shirong Li Suzanne Lentzsch

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