Robert Orlowski, Deputy Chair of Lymphoma/Myeloma, Vice Chair of MM Research, and Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, shared a post on X:
“Myeloma Paper of the Day:
Unique N-glycosylation pattern of anti-MAG IgM (dominated by fucosylated, monosialylated N-glycan with bisecting N-acetyl glucosamine) is crucial for its interaction with MAG, binding to C1q, and inflammatory cytokine production.”
Title: N-Glycan–Dependent Proinflammatory Effects of IgM in Anti-MAG Neuropathy
Authors: Jean Neil, François Fenaille, Arnaud Bruneel, Tanya Stojkovic, Sophie Cholet, Emilien Delmont, Pauline Ober, Alexandre Raynor, Quentin Amiot, Karim Dorgham, Karine Viala, Pascale Ghillani-Dalbin, Guy Gorochov, Delphine Sterlin
You can read the Full Article on Neurology: Neuroimmunology and Neuroinflammation.
You can find more posts featuring Robert Orlowski on OncoDaily.
