
May 20, 2025, 09:15
Myeloma Paper of the Day, May 20th, suggested by Robert Orlowski
Robert Orlowski, Deputy Chair of Lymphoma/Myeloma, Vice Chair of MM Research and Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, shared a post on X:
“Myeloma Paper of the Day: Single center study of dual BCMA/GPRC5D bispecific CAR T finds a somewhat disappointing 44.4% (4/9) CR rate, 1-year OS and PFS rates of 60% and 63%, respectively, though all pts had EMD at baseline.”
Title: BCMA/GPRC5D bispecific CAR T-cell therapy for relapsed/refractory multiple myeloma with extramedullary disease: a single-center, single-arm, phase 1 trial
Authors: Hao Yao, Shi-hui Ren, Lin-hui Wang, Ming-qiang Ren, Jiao Cai, Dan Chen, Ying He, Si-han Lai, Bai-tao Dou, Meng-jiao Li, Yan-ling Li, Ya-li Cen, Alex H. Chang, Yi Su, Ling Qiu, Fang-yi Fan.
You can read the Full Article in Journal of Hematology and Oncology.
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