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Myeloma Paper of the Day, March 9th, suggested by Robert Orlowski
Mar 9, 2025, 10:27

Myeloma Paper of the Day, March 9th, suggested by Robert Orlowski

Robert Orlowski, Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, shared a post on X:

“Myeloma Paper of the Day: ACC1 (Acetyl-CoA carboxylase) is a metabolic vulnerability in MYC-driven myeloma and inhibiting ACC1 disrupts lipid homeostasis, induces ER stress, and causes oxidative damage, impairing cell survival.”

“­­­­­Targeting Acetyl-CoA Carboxylase Suppresses De Novo Lipogenesis and Tumor Cell Growth in Multiple Myeloma”

Authors: Eugenio Morelli, Caroline Fidalgo Ribeiro, Silvia Rodrigues, Nikhil Munshi, Massimo Loda et al.

Myeloma Paper of the Day, March 9th, suggested by Robert Orlowski

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