Science

Raymond Chan: Morning Fatigue Severity in Oncology Patients Receiving Chemotherapy

Raymond Chan/X

Jul 30, 2025, 10:22

Raymond Chan: Morning Fatigue Severity in Oncology Patients Receiving Chemotherapy

Raymond Chan, Deputy Vice-Chancellor of Research at Flinders University, shared a post on LinkedIn about a paper he co-authored with colleagues published in Cancer Medicine:

“Sharing latest research published in Cancer Medicine led by Dr Kord M. Kober:

‘A Data‐Driven Epigenetic Characterization of Morning Fatigue Severity in Oncology Patients Receiving Chemotherapy’

This work reflects a strong collaboration across institutions and disciplines – including nursing, genomics, oncology, and bioinformatics.

Fatigue is one of the most debilitating symptoms for patients undergoing chemotherapy. In this study, our team used a data-driven approach to explore how epigenetic age acceleration, blood cell composition, and methylation patterns relate to morning fatigue severity.

Key findings:

Patients with higher epigenetic age acceleration were more likely to experience severe morning fatigue.
Distinct biological profiles may help identify patients at risk and guide targeted interventions.”

Title: A Data-Driven Epigenetic Characterization of Morning Fatigue Severity in Oncology Patients Receiving Chemotherapy: Associations With Epigenetic Age Acceleration, Blood Cell Types, and Expression-Associated Methylation

Authors: Caroline Le, Maureen Lewis, Carolyn S. Harris, Liam Berger, Esther Chavez-Iglesias, Lisa Morse, Anatol Sucher, Ritu Roy, Adam Olshen, Marilyn J. Hammer, Steve Paul, Margaret Wallhagen, Raymond Chan, Michael Sayer, Sue Yom, Nam-Woo Cho, Alexandre Chan, Jon Levine, Anand Dhruva, Christine Miaskowski, Yvette P. Conley, Kord M. Kober

You can read the full article on Cancer Medicine.

Cancer Medicine