Jarushka Naidoo, Full Professor and Consultant Medical Oncologist at Royal College of Surgeons in Ireland, shared a post on LinkedIn:
“‘CSF-BAM:’
A novel method to detect brain metastases/leptomeningeal disease/primary brain tumours?
– integrates B cell, T cell, aneuploidy + tDNA in CSF
– 81% sensitivity 100% specificity for cancer
Pleased to contribute to this paper led by CHETAN BETTEGOWDA Johns Hopkins Medicine.”
Title: Detection of human brain cancers using genomic and immune cell characterization of cerebrospinal fluid through CSF-BAM
Authors: Alexander H. Pearlman, Yuxuan Wang, Anita Kalluri, Megan Parker, Joshua D. Cohen, Jonathan Dudley, Jordina Rincon-Torroella, Yuanxuan Xia, Ryan Gensler, Melanie Alfonzo Horowitz, John N. Theodore, Lisa Dobbyn, Maria Popoli, Janine Ptak, Natalie Silliman, Kathy Judge, Peter A. Calabresi, Mari Groves, Christopher M. Jackson, Eric M. Jackson, George I Jallo, Michael Lim, Mark Luciano, Debraj Mukherjee, Jarushka Naidoo, Sima Rozati, Cole H. Sterling, Jon Weingart, Carl Koschmann, Alireza Mansouri, Michael Glantz, David Kamson, Karisa C. Schreck, Carlos A. Pardo, Matthias Holdhoff, Maximilian F. Konig, Suman Paul, Kenneth W. Kinzler, Nickolas Papadopoulos, Bert Vogelstein, Christopher Douville, Chetan Bettegowda
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