Enrique Grande: 25-Year NCI Study Highlights Indolent Growth Patterns in Bilateral Multifocal Papillary RCC
Enrique Grande/ X

Enrique Grande: 25-Year NCI Study Highlights Indolent Growth Patterns in Bilateral Multifocal Papillary RCC

Enrique Grande, One Oncology Madrid Program Director at Quironsalud, shared on X:

“On European Urology 25-yr prospective NCI cohort of sporadic bilateral multifocal papillary RCC (n=89).

Growth was predominantly indolent (median 1.55 mm/yr). Metastases occurred only in patients whose largest tumor exceeded 3 cm. Repeat ipsilateral partial nephrectomy was associated with a decline in renal function.

Findings are consistent with active surveillance for small renal masses and nephron-sparing surgery when intervention is needed.”

Title: Natural History, Tumor Growth Kinetics, and Renal Functional Outcomes of Sporadic Bilateral Multifocal Papillary Renal Cell Carcinoma: A 25-yr Prospective Cohort Study

Authors: Hangcheng Fu, Ruben Blachman-Braun, Lauren Loebach, Jeunice Owens-Walton, Braden Millan, Patrick Michael, Milan Patel, Cathy D. Vocke, Christopher J. Ricketts, Laura S. Schmidt, Rabindra Gautam, Maria J. Merino, Sandeep Gurram, W. Marston Linehan, Mark W. Ball

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Enrique Grande: 25-Year NCI Study Highlights Indolent Growth Patterns in Bilateral Multifocal Papillary RCC