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Elli Papaemmanuil: Tumor-Infiltrating Clonal Hematopoiesis
mskcc.org
Apr 26, 2025, 10:37

Elli Papaemmanuil: Tumor-Infiltrating Clonal Hematopoiesis

Elli Papaemmanuil, Co-Founder and CEO of Isabl and Associate Professor of Computational Oncology Service at MSKCC, shared a post on X by Eric Topol, Founder and Director of the Scripps Research Translational Institute, about a paper she co-authored with colleagues published in NEJM:

“Tumor-Infiltrating Clonal Hematopoiesis”

Authors: Oriol Pich, Elsa Bernard, Maria Zagorulya, Andrew Rowan, Constandina Pospori, Charles Rudin, Adam Mead, Dominique Bonnet, Elli Papaemmanuil, Charles Swanton et al.

Elli Papaemmanuil: Tumor-Infiltrating Clonal Hematopoiesis

“It has been unclear why cancer patients with CH have worse outcomes. Our work published in NEJM uncovers that Tumour-infiltrating CH (TI-CH) has a direct role in immune remodelling of the TME with implications for tumor progression and treatment response.”

Quoting Eric Topol’s post:

“New evidence today in NEJM that age-related clonal hematopoiesis (CHIP) has a driver role in evolution of solid cancers.”

Elli Papaemmanuil: Tumor-Infiltrating Clonal Hematopoiesis

Read further.

More posts featuring Eric Topol.

Adam Mead Andrew Rowan cancer Charles Rudin Charles Swanton Constandina Pospori Dominique Bonnet Elli Papaemmanuil Elsa Bernard Eric Topol Maria Zagorulya NEJM OncoDaily Oncology Oriol Pich TI-CH Tumour-infiltrating CH
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