
Alexey Kulikov/LinkedIn
Jun 19, 2025, 15:50
Alexey Kulikov Shared An Article on Cancer Vaccines and The Future of Immunotherapy
Alexey Kulikov, Head of Partnerships and Operations, Deputy Head of Secretariat for the UN NCD Task Force, and an External Relations Officer at WHO, shared a post on LinkedIn:
“Check this recent piece at The Lancet Group on Cancer vaccines and the future of immunotherapy.
Therapeutic vaccines training the immune system to eliminate established tumours are now showing real promise in clinical settings. In the adjuvant setting, vaccines against melanoma and pancreatic cancer appear to be reducing minimal residual disease and relapse. In the macrometastatic setting, in-situ vaccines have induced systemic regressions in advanced-stage lung and breast cancers and lymphomas.
More effective cancer vaccines are being developed through having a deeper understanding of crucial cellular factors in tumour immunology, the incorporation of newer vaccine components to effectively mobilise and activate cells, the use of omics and artificial intelligence in vaccine design, and addition of immune checkpoint blockade.
Review analyses cancer vaccine trials, the strengths and limitations of different vaccine approaches, and discuss how the next generation of cancer vaccines can help improve patient outcomes and quality of life.”
Title: Cancer vaccines and the future of immunotherapy
Authors: Orrin Pail, Matthew J Lin, Theodora Anagnostou, Brian D Brown, Joshua D Brody
You can read the Full Article on The Lancet Journal
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