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Antonio Giordano: Why Do DXd-ADCs Cause ILD Regardless of Target?
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Antonio Giordano: Why Do DXd-ADCs Cause ILD Regardless of Target?

Antonio Giordano, Clinical Director at Dana-Farber Cancer Institute, shared on X:

“Why do DXd-ADCs cause ILD regardless of target?

ILD tracks with the DXd payload + IgG1 backbone — HER2, TROP2, HER3 alike. It’s OFF-target, not on-target/off-tumor. Dr. Vamsi Velcheti.”

Antonio Giordano: Why Do DXd-ADCs Cause ILD Regardless of Target?

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