Anthony Letai, Director of the National Cancer Institute (NCI), shared on X:
“I am a strong supporter of human-relevant cancer models.
New research, funded in part by NIH, adds ~150 3D organoids across 10 cancer types to DepMap-preserving tumor biology that 2D lines miss and revealing drug targets that might never have been found.”
Title: A dependency map enhanced with next-generation 3D cancer models
Authors: James V. Neiswender, Samuel Maffa, Lisa Brenan, Dina ElHarouni, Yejie Yun, Isabella Boyle, Kirsty Wienand, Haider Inam, Tate Bertea, Ashley Anderson, Megan Wong, Matias Enriquez, Evan Lenz, Beatriz Villafranca, Nora Shanks, Mary Hager, Nia Lloyd, Hannah Shadmany, Sarah J. Wie, Harry Liang, Konnor Yunghans, Xiaomeng Zhang, Lauren Golden, Hannah Harris, Serena Day, Philip Montgomery, Samantha Stokes, Ross M. Giglio, Cynthia Hajal, James R. Whittle, Guadalupe Garcia, Caitlin E. Mills, Mehdi Touat, Kristine Pelton, Hongyu Li, Prem Sai Prabhakar, Sonja Herter, Zoe Hoffmann Kamrat, Dan Gui, Julien Dilly, Chen Khuan Wong, Jimmy A. Guo, Sangita Pal, Yossef Baidi, Ryan Johnston, Daniel D. Brown, Sonam Bhatia, Peter S. Winter, Srivatsan Raghavan, Rameen Beroukhim, Eva Colas, David L. Spector, Adam J. Bass, Peter K. Sorger, Yu Chen, Sarah J. Hill, Steffi Oesterreich, Adrian V. Lee, Himisha Beltran, Jesse S. Boehm, Yuen-Yi Tseng, David E. Root, William C. Hahn, Andrew J. Aguirre, Catarina D. Campbell, Keith L. Ligon, Joshua M. Dempster, Tsukasa Shibue, Francisca Vazquez.
Other articles about Anthony Letai on OncoDaily.
See also: The 100 Most Influential People in Oncology in 2025 (Full List)
Anthony Letai was recognized among OncoDaily’s The 100 Most Influential People in Oncology in 2025, highlighting his contributions to the field of oncology.
Nominations for 100 Influential People in Oncology 2026 are now open, recognizing leaders, researchers, clinicians, innovators, advocates, and other individuals making a meaningful impact on oncology and cancer care.
Don’t miss the opportunity to nominate yourself, a colleague, or someone whose contributions deserve to be recognized.
Submit your nomination by September 15.
