Stephanie Lim, Medical Oncologist at Macarthur Cancer Therapy Centre and GenesisCare; Clinician Researcher at Ingham Institute for Applied Medical Research; Conjoint Associate Professor at Western Sydney University, shared on LinkedIn:
“Young-onset colorectal cancer: Is it a different disease?
The rising incidence of colorectal cancer in young adults is concerning, particularly in those under 35.
Great to see Alexandra Thoms presenting our research at COSA2026, exploring the clinicopathological characteristics of young and very young-onset colorectal cancer in culturally diverse South Western Sydney Local Health District.
This complements our recent collaborative publication with the TRACC registry, BioGrid Australia Limited led by Colin Williams, Azim Jalali and Peter Gibbs, highlighting some striking findings in patients diagnosed before 35:
- BRAF V600E mutations: 32% vs 10% in those aged 35–49
- dMMR tumours: 9.8% vs 2.8%
- More de novo metastatic disease: 79% vs 70%”
Title: Metastatic Colorectal Cancer Diagnosed Before Age 35: A Distinct Subset of Early-Onset Disease?
Authors: Colin Williams, Azim Jalali, Samuel Smith, Sue-Anne McLachlan, Matthew Burge, Stephanie Hui-Su Lim, Susan Caird, Grace Y. Kim, Adnan Khattak, Belinda Lee, Louise Nott, Ross Jennens, Simone Steel, Brigette Ma, Shehara Mendis, Jeremy Shapiro, Rachel Wong, Michael Harold, Vanessa Wong, Peter Gibbs
Read the Full Article on International Journal of Cancer
About COSA 2026
COSA stands for the Clinical Oncology Society of Australia, the peak multidisciplinary professional organisation for cancer care and oncology research in Australia.The organisation brings together medical oncologists, radiation oncologists, surgeons, cancer nurses, researchers, allied health professionals, and other specialists involved in cancer prevention, treatment, and supportive care.
Its annual scientific meeting provides a platform for:
- Presenting the latest cancer research and clinical findings.
- Discussing advances in cancer diagnosis and treatment.
- Sharing clinical experience and best practices.
- Encouraging collaboration among oncology professionals and researchers.
- Highlighting emerging challenges and developments in cancer care.
Learn more about COSA 2026 on OncoDaily
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