Aishee Pal Sadhu։ Predicting CAR-T Toxicity Risk Through CAR-HEMATOTOX and EASIX Scores
Aishee Pal Sadhu/LinkedIn

Aishee Pal Sadhu։ Predicting CAR-T Toxicity Risk Through CAR-HEMATOTOX and EASIX Scores

Aishee Pal Sadhu, Medical Advisor and Manager, Medical Team, Delhi NCR, North Zone at ImmunoACT, shared on LinkedIn:

“CAR T series. Episode 3. | CAR HEMATOX and EASIX tool

CAR-T Physiology Pearls | Translating Physiology into Precision Cellular Therapy

Would you infuse CAR-T into a patient with a 5x higher risk of severe toxicity if you knew it beforehand?

Most CAR-T discussions focus on efficacy.

Far fewer focus on predicting who may develop severe CRS, ICANS, or prolonged cytopenias before infusion.

Two physiology-driven tools are helping answer that question:

  • CAR-HEMATOTOX Score
  • EASIX Score

What fascinates me is that these scores remind us of something fundamental:

Physiology speaks before clinical deterioration becomes visible.

The future of precision oncology is not only about selecting the right therapy.
It is about selecting the right monitoring strategy for the right patient at the right time.

Working at the intersection of clinical science, physiology, and advanced cellular therapies has taught me that the most powerful innovations are often the ones that help us anticipate problems before they happen.

Prediction is prevention.
And prevention saves lives.

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