Rachit Khandelwal/X
Apr 27, 2025, 10:55
Rachit Khandelwal: Glucarpidase for treatment of high-dose methotrexate toxicity
Rachit Khandelwal, Pediatrics BMT fellow at Medanta The Medicity, shared an article by Shruti Gupta, et al. on X:
“Glucarpidase for treatment of high-dose methotrexate toxicity.
MTX-AKI? Think glucarpidase.
In a multicenter study (n=708), glucarpidase use was linked to:
- 2.7x ↑ kidney recovery.
- Faster renal recovery (aHR 1.88).
- ↓ grade ≥2 neutropenia & transaminitis.
- No change in mortality.
A potential game-changer in managing MTX toxicity.”
Glucarpidase for treatment of high-dose methotrexate toxicity.
Authors: Shruti Gupta, et al.
-
Challenging the Status Quo in Colorectal Cancer 2024
December 6-8, 2024
-
ESMO 2024 Congress
September 13-17, 2024
-
ASCO Annual Meeting
May 30 - June 4, 2024
-
Yvonne Award 2024
May 31, 2024
-
OncoThon 2024, Online
Feb. 15, 2024
-
Global Summit on War & Cancer 2023, Online
Dec. 14-16, 2023
Apr 27, 2025, 14:42
Apr 27, 2025, 13:45
Apr 27, 2025, 13:34
Apr 27, 2025, 13:21