Yan Leyfman
Apr 13, 2025, 13:30
Yan Leyfman: Can we treat resectable pancreatic cancer without surgery?
Yan Leyfman, Co-founder and executive director of MedNews Week, shared an article by Marsha Reyngold, et al. on LinkedIn:
“Can we treat resectable pancreatic cancer without surgery?
In a study of 25 patients with technically resectable PDAC who couldn’t undergo surgery, definitive ablative radiation therapy (A-RT) delivered:
- 2-year overall survival: 43.7%.
- Local progression rate: 20.8%.
- Minimal grade 3+ toxicity.
- Strong tumor control in older, frail patients.
A-RT may be a viable non-surgical option for localized pancreatic cancer—especially when surgery is high-risk or functionally debilitating.”
Nonoperative Management of Technically Resectable Pancreatic Cancer With Ablative Radiation Therapy.
Authors: Marsha Reyngold, et al.
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