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Armando Orlandi: NA-PHER2 study shows HER2+/ER+ breast cancers can be treated without chemotherapy
Mar 6, 2025, 10:57

Armando Orlandi: NA-PHER2 study shows HER2+/ER+ breast cancers can be treated without chemotherapy

Armando Orlandi, Medical Oncologist at Agostino Gemelli University Policlinic, shared an article by Maurizio Callari, et al. on X:

“Cowabunga!

Riding Breast Cancer‘s Biggest Data’s Wave from Literature.

NA-PHER2 study shows HER2+/ER+ breast cancers can be treated without chemo!

High TIL + low ER signaling = 72.7% pCR. TP53 mutations spell trouble though!

Targeting PAK4 for RD?”

Determinants of response and molecular dynamics in HER2+ER+ breast cancers from the NA-PHER2 trial receiving HER2-targeted and endocrine therapies.

Authors: Maurizio Callari, et al.

Armando Orlandi: NA-PHER2 study shows HER2+/ER+ breast cancers can be treated without chemotherapy