Nelson Dusetti: Investigating how the pancreatic tumor microenvironment affects γδ T cells
Nelson Dusetti, Head of the Department of Translational Research and Innovative Therapies at CRCM, shared a post on LinkedIn about recent paper by Elena Lo Presti et al., titled “The pancreatic tumor microenvironment of treatment-naïve patients causes a functional shift in γδ T cells, impairing their anti-tumoral defense” published on Taylor and Francis.
Authors: Elena Lo Presti, Francesca Cupaioli, Daniela Scimeca, Elettra Unti, Vincenzo Di Martino, Rossella Daidone, Michele Amata, Nunzia Scibetta, Erinn Soucie, Serena Meraviglia, Juan Iovanna, Nelson Dusetti, Andrea De Gaetano, Ivan Merelli, and Roberto Di Mitri
“It was a pleasure to contribute to this work, and congratulations to Elena Lo Presti and all co-authors on this fantastic collaboration!
Last year, we had the pleasure of hosting Elena in Marseille, where she worked closely with our team. Her stay was a valuable experience for us, and we are thrilled to see her research now published.
‘The pancreatic tumor microenvironment of treatment-naïve patients causes a functional shift in γδ T cells, impairing their anti-tumoral defense.’
This study investigates how the pancreatic tumor microenvironment affects γδ T cells, shifting them into a dysfunctional state that hinders their anti-tumor activity. These findings provide key insights into the immunosuppressive mechanisms in pancreatic cancer, paving the way for potential new therapeutic strategies.
We were delighted to be part of this work!”
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