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Alberto Martini: Oncologic surveillance after surgical treatment for clinically localized kidney cancer
Dec 17, 2024, 20:55

Alberto Martini: Oncologic surveillance after surgical treatment for clinically localized kidney cancer

Alberto Martini, Assistant Professor and Director of Research at the Division of Urology at University of Cincinnati, posted the following on X:

“Long overdue, but finally out:

Oncologic surveillance after surgical treatment for clinically localized kidney cancer: UroCCR 129.

In 2021, the European Association of Urology EAU Guidelines implemented a novel, expert opinion-based follow-up scheme, with a three-risk-category system.

For clear cell (cc) and non-cc renal cell carcinoma (non-ccRCC) after surgery with curative intent.
In our study, we aimed to validate the follow-up scheme and provide data-driven recurrence estimates according to risk groups, to confirm or implement the surveillance strategy

We identified 5,320 patients from a prospectively maintained database involving 28 French referral centers. The risk of recurrence, as either loco-regional or distant, was evaluated for each group (low- intermediate- or high-risk) according to ccRCC or non-ccRCC histology.

Based on the low recurrence risk of patients with intermediate risk non-clear cell histology, patients falling in this category could be followed up with a similar strategy to those falling in the low-risk category.

Alberto Martini: Oncologic surveillance after surgical treatment for clinically localized kidney cancer

Similarly, patients with high-risk non-clear cell histology with negative imaging at 3 months, could be followed up similarly to individuals with clear cell disease falling in the intermediate risk group after the 3-month time point.

Alberto Martini: Oncologic surveillance after surgical treatment for clinically localized kidney cancer

We proposed a revision of the oncologic surveillance intensity to the current EAU follow-up scheme. Our proposed revision of the follow-up strategy could potentially result in lower imaging per patient, hence reducing follow-up related costs and radiation exposure.

Alberto Martini: Oncologic surveillance after surgical treatment for clinically localized kidney cancer