Jason Vassy: Can a clinical polygenic model improve prostate cancer screening?
Jason Vassy, Associate Professor of Medicine at Harvard Medical School and a physician-investigator at VA Boston Healthcare System, shared on X:
“Can a clinical polygenic model improve prostate cancer screening?
We now describe our P-CARE model and its application in the new ProGRESS clinical trial:
From a genomic risk model to clinical trial implementation in a learning health system.”
Authors: Jason L Vassy, Anna M Dornisch, Roshan Karunamuni, Michael Gatzen, Christopher J Kachulis, Niall J Lennon, Charles A Brunette, Morgan E Danowski, Richard L Hauger, Isla P Garraway, Adam S Kibel, Kyung Min Lee, Julie A Lynch, Kara N Maxwell, Brent S Rose, Craig C Teerlink, George J Xu, Sean E Hofherr, Katherine A Lafferty, Katie Larkin, Edyta Malolepsza, Candace J Patterson, Diana M Toledo, Jenny L Donovan, Freddie Hamdy, Richard M Martin, David E Neal, Emma L Turner, Ole A Andreassen, Anders M Dale, Ian G Mills, Jyotsna Batra, Judith Clements, Olivier Cussenot, Cezary Cybulski, Rosalind A Eeles, Jay H Fowke, Eli Marie Grindedal, Robert J Hamilton, Jasmine Lim, Yong-Jie Lu, Robert J MacInnis, Christiane Maier, Lorelei A Mucci, Luc Multigner, Susan L Neuhausen, Sune F Nielsen, Marie-Élise Parent, Jong Y Park, Gyorgy Petrovics, Anna Plym, Azad Razack, Barry S Rosenstein, Johanna Schleutker, Karina Dalsgaard Sørensen, Ruth C Travis, Ana Vega, Catharine M L West, Fredrik Wiklund, Wei Zheng, Profile Steering Committee, IMPACT Study Steering Committee and Collaborators, PRACTICAL Consortium, Million Veteran Program, Tyler M Seibert
Jason Vassy, MD, MPH, is an Associate Professor of Medicine at Harvard Medical School and a physician-investigator at VA Boston Healthcare System. He is also a member of the Precision Population Health initiative at Ariadne Labs and Brigham and Women’s Hospital. As the Director of the Genomes2Veterans program, Dr. Vassy is a primary care internist and researcher focused on implementing and evaluating genomic medicine interventions in clinical settings.
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