Ilyas Sahin: Two Important Cancer Studies
Ilyas Sahin, Medical Oncologist at Massachusetts General Hospital, shared on X:
“Two important cancer studies in Nature this week.
- Selective NSD2 inhibitors reverse abnormal chromatin states and suppress KRAS-mutant lung and pancreatic tumors, especially in combination with sotorasib.
Title: NSD2 inhibitors rewire chromatin to treat lung and pancreatic cancers
Authors: Jinho Jeong, Simone Hausmann, Hanyang Dong, Kacper Szczepski, Natasha M. Flores, Andy Garcia Gonzalez, Liyang Shi, Xiaoyin Lu, Joanna Lempiäinen, Moritz Jakab, Liyong Zeng, Tourkian Chasan, Eric Bareke, Rui Dong, Emma Carlson, Reinnier Padilla, Dylan Husmann, Julia Thompson, Gerry A. Shipman, Emily Zahn, Courtney A. Barnes, Laiba F. Khan, Liz Marie Albertorio-Sáez, Eva Brill, Vishnu Udayakumar Sunita Kumary, Matthew R. Marunde, Danielle N. Maryanski, Cheryl C. Szany, Bryan J. Venters, Carolina Lin Windham, Michal Eligiusz Nowakowski, Iwona Czaban, Mariusz Jaremko, Michael-Christopher Keogh, Kang Le, Michael J. Soth, Benjamin A. Garcia, Łukasz Jaremko, Jacek Majewski, Pawel K. Mazur and Or Gozani
- Persistent excised DNA circles are linked to relapse in childhood leukemia, offering a novel biomarker.”
Title: Excised DNA circles from V(D)J recombination promote relapsed leukaemia
Authors: Zeqian Gao, James N. F. Scott, Matthew P. Edwards, Dylan Casey, Xiaoling Wang, Andrew D. Gillen, Sarra Ryan, Lisa J. Russell, Anthony V. Moorman, Ruth de Tute, Catherine Cargo, Anthony M. Ford, David R. Westhead and Joan Boyes
More posts featuring Ilyas Sahin.
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Challenging the Status Quo in Colorectal Cancer 2024
December 6-8, 2024
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ESMO 2024 Congress
September 13-17, 2024
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ASCO Annual Meeting
May 30 - June 4, 2024
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Yvonne Award 2024
May 31, 2024
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OncoThon 2024, Online
Feb. 15, 2024
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Global Summit on War & Cancer 2023, Online
Dec. 14-16, 2023