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Erman Akkus: Can ctDNA clearance predict pCR in neoadjuvant IO?
Erman Akkus/X
Apr 5, 2025, 14:21

Erman Akkus: Can ctDNA clearance predict pCR in neoadjuvant IO?

Erman Akkus, Medical Oncology Fellow at Ankara University, shared an article by C. Valenza, et al. on X:

“Can ctDNA clearance predict pCR in neoadjuvant IO?

– Sensitivity 0.98, but
– Specificity 0.53

Should not rely on ctDNA clearance to inform treatment decisions.”

Circulating tumor DNA Clearance as a Predictive Biomarker of Pathologic Complete Response in Patients with Solid Tumors Treated with Neoadjuvant Immune-Checkpoint Inhibitors: a Systematic Review and Meta-Analysis

Authors: C. Valenza et al.

Erman Akkus

cancer Curigliano Giuseppe Erman Akkus OncoDaily Oncology
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