Photo from Olubukola Ayodele/LinkedIn
Oct 21, 2023, 19:24
Olubukola Ayodele: Day 1 of ESMO 2023 was all about early breast cancer (EBC) for me today
Olubukola Ayodele, Consultant Medical Oncologist at University Hospitals of Leicester NHS trust, shared on LinkedIn:
“Day 1 of ESMO 2023 is over.
It was all about early breast cancer (EBC) for me today.
- MonarchE continues to show benefit with adjuvant Abemaciclib in HR+/HER2- EBC. Median follow up 54 months. All patients have completed 2 years of treatment. Close follow up needed as this cohort tend to relapse after the 5 year mark.
- KN522 also continues to show benefit of the addition of pembrolizumab to chemotherapy for TNBC irrespective of stage.
- New territory: Neoadjuvant immunotherapy in combination with chemotherapy in high risk HR+/HER2- EBC. pCR benefit seen but will it translate to EFS? Also, higher benefit seen in PD-L1 + patients. Would this influence the FDA/EMA approval if benefit is consistent?
More biomarker analysis needed to better select patients in EBC.
However, I’m so happy to see more potential treatment options for patients.”
Source: Olubukola Ayodele/LinkedIn
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