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Triparna Sen: Molecular Landscape and Therapeutic Strategies of Lung Cancer Lineage Plasticity
Aug 23, 2025, 14:15

Triparna Sen: Molecular Landscape and Therapeutic Strategies of Lung Cancer Lineage Plasticity

Triparna Sen, Professor at The Ohio State University, shared on X about a recent paper she co-authored with colleagues, published in JTO:

“Excited to share our review on ‘Molecular Landscape and Therapeutic Strategies of Lung Cancer Lineage Plasticity’ in JTO.

We examine how LUAD transforms into SCLC or LUSC under treatment pressure as a key factor in resistance, and unpack the genetic, epigenetic, and immune programs that drive this evolution.

Understanding these histologic switches opens the way for new therapeutic targets to prevent or stop tumor escape.

So proud to have collaborated with an amazing and fun team of friends and collaborators – Avisek Banerjee, Ioannis Vathiotis, Fred R. Hirsch, Kostas Syrigos, Misty Dawn Shields, Utsav Sen, Raj Veluswamy, Xuejun Wang, Debdatta Halder.”

Triparna Sen

Title: Molecular Landscape and Therapeutic Strategies of Lung Cancer Lineage Plasticity

Journal: JTO

Authors: Avisek Banerjee, Ioannis Vathiotis, Debdatta Halder, Utsav Sen, Xuejun Wang, Misty D. Shields, Rajwanth R. Veluswamy, Konstantinos Syrigos, Fred R. Hirsch, Triparna Sen

Read the full article.

Triparna Sen

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