Trastuzumab Deruxtecan in Advanced Solid Tumors With HER 2 Amplification Identified
Arndt Vogel, Managing Senior Consultant and a Professor in the Department of Gastroenterology, shared an article by Masataka Yagisawa on X:
“Trastuzumab Deruxtecan in Advanced Solid Tumors With HER2 Amplification Identified by cfDNA Journal of Clinical Oncology.
- HERALD/EPOC1806 phs II Basket, 61 pts, 16 tumor types.
- ORR 56%, PFS 7.0 mo, DoR 8.8 mo, mOS 14.6 mo.
- cfDNA useful to identify HER2 amplified tumors.”
Authors: Masataka Yagisawa, et al.
Arndt Vogel, MD, is a Managing Senior Consultant and a Professor in the Department of Gastroenterology, Hepatology, and Endocrinology at Hannover Medical School. Leading the GI-Cancer Center and the Center for Personalized Medicine, his research focuses on translational and clinical studies in gastrointestinal cancer. He’s actively engaged in various societies including ESMO, ASCO, and EASL. Additionally, he chairs the Hepatobiliary Cancer Study Group of the AIO, contributing significantly to clinical oncology in Germany. Within ESMO, he serves on the Guidelines Steering Committee.
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